The Run the River Fall Challenge is an annual road race event in Edmonton, Alberta, featuring 5 km, 10 km, and half marathon distances. The races start and finish at Louise McKinney Riverfront Park, winding through Edmonton's scenic river valley pathways. Participants enjoy a post-race BBQ provided by River Valley Adventure Company, with beverages available for purchase. A juniors event with physical literacy activities is also held for kids aged 5 to 12.

- Road surface throughout all race distances
- Start and finish at Louise McKinney Riverfront Park
- Routes follow Edmonton's river valley pathways
- Course rerouted as of September 18, 2025, due to pathway closure west of Walterdale Bridge; runners now cross Walterdale Bridge to turnaround points

- Multiple race distances: 5 km, 10 km, half marathon, and juniors event
- Post-race BBQ by River Valley Adventure Company
- Scenic course along Edmonton's river valley pathways
- Juniors event with physical literacy activities for kids aged 5 to 12